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cchfv np protein  (Native Antigen Inc)


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    Native Antigen Inc cchfv np protein
    <t>CCHFV</t> Gc-specific and <t>CCHFV</t> <t>NP-specific</t> IgG sero-reactivity in sheep sera from endemic CCHFV areas. Sheep sera were collected as part of a cross-sectional study in an endemic CCHFV area (Bulgaria, n = 1,200) and tested for anti-CCHFV Gc-specific IgG levels (A) and anti-CCHFV NP-specific IgG levels (B) by in-house ELISAs. Data are represented as a histogram of the distribution of the OD 450 values frequency (gray bars). Non-parametric estimation of the distribution (solid blue lines) and finite-mixture model (dashed blue lines) with estimated cut-off (red solid line). (C) Relationship between levels of anti-CCHFV Gc-specific and anti-CCHFV NP-specific IgG represented as correlation analysis (Spearman rank test) with red solid lines representing the estimated cut-off by finite mixed model. (D) Heatmap of data normalized across anti-CCHFV Gc and anti-CCHFV NP-specifc IgG using min-max normalization where minimum was defined as the cut-off specific for the assay as descriptive representation of the correlation at individual level. Each row represents data from one animal. Animals below the cut-off represented as gray and animals above the cut-off as different shades of red defined in the legend.
    Cchfv Np Protein, supplied by Native Antigen Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cchfv np protein/product/Native Antigen Inc
    Average 86 stars, based on 1 article reviews
    cchfv np protein - by Bioz Stars, 2026-03
    86/100 stars

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    1) Product Images from "Development of anti-Crimean-Congo hemorrhagic fever virus Gc and NP-specific ELISA for detection of antibodies in domestic animal sera"

    Article Title: Development of anti-Crimean-Congo hemorrhagic fever virus Gc and NP-specific ELISA for detection of antibodies in domestic animal sera

    Journal: Frontiers in Veterinary Science

    doi: 10.3389/fvets.2022.913046

    CCHFV Gc-specific and CCHFV NP-specific IgG sero-reactivity in sheep sera from endemic CCHFV areas. Sheep sera were collected as part of a cross-sectional study in an endemic CCHFV area (Bulgaria, n = 1,200) and tested for anti-CCHFV Gc-specific IgG levels (A) and anti-CCHFV NP-specific IgG levels (B) by in-house ELISAs. Data are represented as a histogram of the distribution of the OD 450 values frequency (gray bars). Non-parametric estimation of the distribution (solid blue lines) and finite-mixture model (dashed blue lines) with estimated cut-off (red solid line). (C) Relationship between levels of anti-CCHFV Gc-specific and anti-CCHFV NP-specific IgG represented as correlation analysis (Spearman rank test) with red solid lines representing the estimated cut-off by finite mixed model. (D) Heatmap of data normalized across anti-CCHFV Gc and anti-CCHFV NP-specifc IgG using min-max normalization where minimum was defined as the cut-off specific for the assay as descriptive representation of the correlation at individual level. Each row represents data from one animal. Animals below the cut-off represented as gray and animals above the cut-off as different shades of red defined in the legend.
    Figure Legend Snippet: CCHFV Gc-specific and CCHFV NP-specific IgG sero-reactivity in sheep sera from endemic CCHFV areas. Sheep sera were collected as part of a cross-sectional study in an endemic CCHFV area (Bulgaria, n = 1,200) and tested for anti-CCHFV Gc-specific IgG levels (A) and anti-CCHFV NP-specific IgG levels (B) by in-house ELISAs. Data are represented as a histogram of the distribution of the OD 450 values frequency (gray bars). Non-parametric estimation of the distribution (solid blue lines) and finite-mixture model (dashed blue lines) with estimated cut-off (red solid line). (C) Relationship between levels of anti-CCHFV Gc-specific and anti-CCHFV NP-specific IgG represented as correlation analysis (Spearman rank test) with red solid lines representing the estimated cut-off by finite mixed model. (D) Heatmap of data normalized across anti-CCHFV Gc and anti-CCHFV NP-specifc IgG using min-max normalization where minimum was defined as the cut-off specific for the assay as descriptive representation of the correlation at individual level. Each row represents data from one animal. Animals below the cut-off represented as gray and animals above the cut-off as different shades of red defined in the legend.

    Techniques Used:

    Correlation and receiver operating characteristic (ROC) analysis of anti-CCHFV Gc-specific and anti-CCHFV NP-specific IgG in-house ELISAs vs. VectoCrimean-CCHF IgG and ID Screen ® CCHF Double Antigen Multi-species commercial kits. A subset of sheep sera collected as part of a cross-sectional study in an endemic CCHFV area ( n =8 0) was tested for anti-CCHFV Gc-specific IgG and anti-CCHFV NP-specific IgG by in-house ELISAs and with VectoCrimean-CHF IgG and ID Screen ® CCHF Double Antigen Multi-species commercial kits. Left panel shows spearman correlations between responses evaluated by: (A) anti-CCHFV Gc-specific IgG in-house ELISA and VectoCrimean-CHF IgG, (B) anti-CCHFV NP-specific IgG in-house ELISA and VectoCrimean-CHF IgG, or (C) ID Screen ® CCHF Double Antigen Multi-species. Right panel shows ROC curves generated using: (A) anti-CCHFV Gc-specific in-house ELISA OD measured at 450 nm and positive ( n = 41) and negative ( n = 39) sera results obtained with VectoCrimean-CHF IgG; (B) anti-CCHFV NP-specific in-house ELISA OD measured at 450 nm and positive ( n = 41) and negative ( n = 39) sera results obtained with VectoCrimean-CHF IgG, or (C) positive ( n = 35) and negative ( n = 45) sera results obtained with ID Screen ® CCHF Double Antigen Multi-species.
    Figure Legend Snippet: Correlation and receiver operating characteristic (ROC) analysis of anti-CCHFV Gc-specific and anti-CCHFV NP-specific IgG in-house ELISAs vs. VectoCrimean-CCHF IgG and ID Screen ® CCHF Double Antigen Multi-species commercial kits. A subset of sheep sera collected as part of a cross-sectional study in an endemic CCHFV area ( n =8 0) was tested for anti-CCHFV Gc-specific IgG and anti-CCHFV NP-specific IgG by in-house ELISAs and with VectoCrimean-CHF IgG and ID Screen ® CCHF Double Antigen Multi-species commercial kits. Left panel shows spearman correlations between responses evaluated by: (A) anti-CCHFV Gc-specific IgG in-house ELISA and VectoCrimean-CHF IgG, (B) anti-CCHFV NP-specific IgG in-house ELISA and VectoCrimean-CHF IgG, or (C) ID Screen ® CCHF Double Antigen Multi-species. Right panel shows ROC curves generated using: (A) anti-CCHFV Gc-specific in-house ELISA OD measured at 450 nm and positive ( n = 41) and negative ( n = 39) sera results obtained with VectoCrimean-CHF IgG; (B) anti-CCHFV NP-specific in-house ELISA OD measured at 450 nm and positive ( n = 41) and negative ( n = 39) sera results obtained with VectoCrimean-CHF IgG, or (C) positive ( n = 35) and negative ( n = 45) sera results obtained with ID Screen ® CCHF Double Antigen Multi-species.

    Techniques Used: Enzyme-linked Immunosorbent Assay, Generated



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    Image Search Results


    CCHFV Gc-specific and CCHFV NP-specific IgG sero-reactivity in sheep sera from endemic CCHFV areas. Sheep sera were collected as part of a cross-sectional study in an endemic CCHFV area (Bulgaria, n = 1,200) and tested for anti-CCHFV Gc-specific IgG levels (A) and anti-CCHFV NP-specific IgG levels (B) by in-house ELISAs. Data are represented as a histogram of the distribution of the OD 450 values frequency (gray bars). Non-parametric estimation of the distribution (solid blue lines) and finite-mixture model (dashed blue lines) with estimated cut-off (red solid line). (C) Relationship between levels of anti-CCHFV Gc-specific and anti-CCHFV NP-specific IgG represented as correlation analysis (Spearman rank test) with red solid lines representing the estimated cut-off by finite mixed model. (D) Heatmap of data normalized across anti-CCHFV Gc and anti-CCHFV NP-specifc IgG using min-max normalization where minimum was defined as the cut-off specific for the assay as descriptive representation of the correlation at individual level. Each row represents data from one animal. Animals below the cut-off represented as gray and animals above the cut-off as different shades of red defined in the legend.

    Journal: Frontiers in Veterinary Science

    Article Title: Development of anti-Crimean-Congo hemorrhagic fever virus Gc and NP-specific ELISA for detection of antibodies in domestic animal sera

    doi: 10.3389/fvets.2022.913046

    Figure Lengend Snippet: CCHFV Gc-specific and CCHFV NP-specific IgG sero-reactivity in sheep sera from endemic CCHFV areas. Sheep sera were collected as part of a cross-sectional study in an endemic CCHFV area (Bulgaria, n = 1,200) and tested for anti-CCHFV Gc-specific IgG levels (A) and anti-CCHFV NP-specific IgG levels (B) by in-house ELISAs. Data are represented as a histogram of the distribution of the OD 450 values frequency (gray bars). Non-parametric estimation of the distribution (solid blue lines) and finite-mixture model (dashed blue lines) with estimated cut-off (red solid line). (C) Relationship between levels of anti-CCHFV Gc-specific and anti-CCHFV NP-specific IgG represented as correlation analysis (Spearman rank test) with red solid lines representing the estimated cut-off by finite mixed model. (D) Heatmap of data normalized across anti-CCHFV Gc and anti-CCHFV NP-specifc IgG using min-max normalization where minimum was defined as the cut-off specific for the assay as descriptive representation of the correlation at individual level. Each row represents data from one animal. Animals below the cut-off represented as gray and animals above the cut-off as different shades of red defined in the legend.

    Article Snippet: CCHFV Gc protein and CCHFV NP protein (strain IbAr10200, Nigeria, 1996) were produced in HEK293 cells (The Native Antigen Company, REC31696 and REC31639, respectively).

    Techniques:

    Correlation and receiver operating characteristic (ROC) analysis of anti-CCHFV Gc-specific and anti-CCHFV NP-specific IgG in-house ELISAs vs. VectoCrimean-CCHF IgG and ID Screen ® CCHF Double Antigen Multi-species commercial kits. A subset of sheep sera collected as part of a cross-sectional study in an endemic CCHFV area ( n =8 0) was tested for anti-CCHFV Gc-specific IgG and anti-CCHFV NP-specific IgG by in-house ELISAs and with VectoCrimean-CHF IgG and ID Screen ® CCHF Double Antigen Multi-species commercial kits. Left panel shows spearman correlations between responses evaluated by: (A) anti-CCHFV Gc-specific IgG in-house ELISA and VectoCrimean-CHF IgG, (B) anti-CCHFV NP-specific IgG in-house ELISA and VectoCrimean-CHF IgG, or (C) ID Screen ® CCHF Double Antigen Multi-species. Right panel shows ROC curves generated using: (A) anti-CCHFV Gc-specific in-house ELISA OD measured at 450 nm and positive ( n = 41) and negative ( n = 39) sera results obtained with VectoCrimean-CHF IgG; (B) anti-CCHFV NP-specific in-house ELISA OD measured at 450 nm and positive ( n = 41) and negative ( n = 39) sera results obtained with VectoCrimean-CHF IgG, or (C) positive ( n = 35) and negative ( n = 45) sera results obtained with ID Screen ® CCHF Double Antigen Multi-species.

    Journal: Frontiers in Veterinary Science

    Article Title: Development of anti-Crimean-Congo hemorrhagic fever virus Gc and NP-specific ELISA for detection of antibodies in domestic animal sera

    doi: 10.3389/fvets.2022.913046

    Figure Lengend Snippet: Correlation and receiver operating characteristic (ROC) analysis of anti-CCHFV Gc-specific and anti-CCHFV NP-specific IgG in-house ELISAs vs. VectoCrimean-CCHF IgG and ID Screen ® CCHF Double Antigen Multi-species commercial kits. A subset of sheep sera collected as part of a cross-sectional study in an endemic CCHFV area ( n =8 0) was tested for anti-CCHFV Gc-specific IgG and anti-CCHFV NP-specific IgG by in-house ELISAs and with VectoCrimean-CHF IgG and ID Screen ® CCHF Double Antigen Multi-species commercial kits. Left panel shows spearman correlations between responses evaluated by: (A) anti-CCHFV Gc-specific IgG in-house ELISA and VectoCrimean-CHF IgG, (B) anti-CCHFV NP-specific IgG in-house ELISA and VectoCrimean-CHF IgG, or (C) ID Screen ® CCHF Double Antigen Multi-species. Right panel shows ROC curves generated using: (A) anti-CCHFV Gc-specific in-house ELISA OD measured at 450 nm and positive ( n = 41) and negative ( n = 39) sera results obtained with VectoCrimean-CHF IgG; (B) anti-CCHFV NP-specific in-house ELISA OD measured at 450 nm and positive ( n = 41) and negative ( n = 39) sera results obtained with VectoCrimean-CHF IgG, or (C) positive ( n = 35) and negative ( n = 45) sera results obtained with ID Screen ® CCHF Double Antigen Multi-species.

    Article Snippet: CCHFV Gc protein and CCHFV NP protein (strain IbAr10200, Nigeria, 1996) were produced in HEK293 cells (The Native Antigen Company, REC31696 and REC31639, respectively).

    Techniques: Enzyme-linked Immunosorbent Assay, Generated